医药卫生—治疗学

作品数:173243被引量:312650H指数:104
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相关作者:黎介寿黄晓军刘景汉兰炯采吴德沛更多>>
相关机构:中国人民解放军总医院南京军区南京总医院北京协和医院四川大学华西医院更多>>
发文主题:血液透析护理输血疗效观察维持性血液透析患者更多>>
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发文基金:国家自然科学基金国家高技术研究发展计划国家重点基础研究发展计划广东省自然科学基金更多>>
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Effect of lentiviral vector-mediated overexpression of hypoxia-inducible factor 1 alpha delivered by pluronic F-127 hydrogel on brachial plexus avulsion in rats
《中国神经再生研究:英文版》2019年第6期1069-1078,共10页Tao Wang Li-Ni Zeng Zhe Zhu Yu-Hui Wang Lu Ding Wei-Bin Luo Xiao-Min Zhang Zhi-Wei He Hong-Fu Wu 
the National Natural Science Foundation of China,No.81371366(to HFW);the Natural Science Foundation of Guangdong Province of China,No.2015A030313515(to HFW);the Dongguan International Science and Technology Cooperation Project,No.2013508152010(to HFW);the Key Project of Social Development of Dongguan of China,No.20185071521640(to HFW).
Brachial plexus avulsion often results in massive motor neuron death and severe functional deficits of target muscles.However,no satisfactory treatment is currently available.Hypoxia-inducible factor 1αis a critical ...
关键词:NERVE REGENERATION peripheral NERVE injury brachial plexus AVULSION HYPOXIA ischemia hypoxia-inducible factor 1αoverexpression PLURONIC F-127 motor neurons axonal REGENERATION angiogenesis neural REGENERATION 
Neural-like cells from adipose-derived stem cells for cavernous nerve injury in rats
《中国神经再生研究:英文版》2019年第6期1085-1090,共6页Cheng-Cheng Ying1 Mei Yang Yong Wang Yong-Lian Guo Wan-Li Hu Xin-Min Zheng 
the Fundamental Research Funds for the Central Hospital of Wuhan of China,No.YB16A01(to CCY);the Natural Science Foundation of Hubei Province of China,No.2017CFB176(to CCY).
Although the remaining nerve tissue can regenerate and partly restore erectile function when the cavernous nerve is compressed/severed and function lost,the limited regenerative ability of these nerve tissues often fa...
关键词:NERVE REGENERATION adipose-derived NEURAL stem CELLS corpus cavernosum CAVERNOUS NERVE erectile dysfunction radical prostatectomy neurons cell differentiation NEURAL REGENERATION 
Mechanism of persistent hyperalgesia in neuropathic pain caused by chronic constriction injury
《中国神经再生研究:英文版》2019年第6期1091-1098,共8页Qin-Yi Chen Chao-Yang Tan Yang Wang Ke-Tao Ma Li Li Jun-Qiang Si 
the National Natural Science Foundation of China,No.30160026(to JQS);the High Level Talent Research Project of Shihezi University of China,No.RCSX201705(to YW).
Transmembrane member 16A(TMEM16A)is involved in many physiological functions,such as epithelial secretion,sensory conduction,nociception,control of neuronal excitability,and regulation of smooth muscle contraction,and...
关键词:NERVE REGENERATION TMEM16A calcium-activated chloride channels T16Ainh-A01 NEUROPATHIC pain dorsal root ganglia HYPERALGESIA action potential rheobase chronic CONSTRICTION INJURY peripheral NERVE INJURY neural REGENERATION 
Inhibition ofα5 GABAA receptors has preventive but not therapeutic effects on isoflurane-induced memory impairment in aged rats
《中国神经再生研究:英文版》2019年第6期1029-1036,共8页Zi-Fang Zhao Lei Du Teng Gao Lin Bao Yuan Luo Yi-Qing Yin Yong-An Wang 
Theα5 subunit-containing gamma-amino butyric acid type A receptors(α5 GABAARs)are a distinct subpopulation that are specifically distributed in the mammalian hippocampus and also mediate tonic inhibitory currents in...
关键词:ISOFLURANE postoperative cognitive dysfunction hippocampus inverse AGONIST α5 GABAA receptors L-655 708 aged MORRIS Water MAZE memory IMPAIRMENT neural regeneration 
Glutamate receptor delocalization in postsynaptic membrane and reduced hippocampal synaptic plasticity in the early stage of Alzheimer’s disease
《中国神经再生研究:英文版》2019年第6期1037-1045,共9页Ning Li Yang Li Li-Juan Li Ke Zhu Yan Zheng Xiao-Min Wang 
the National Natural Science Foundation of China,No.81571038,81771145(both to YZ).
Mounting evidence suggests that synaptic plasticity provides the cellular biological basis of learning and memory,and plasticity deficits play a key role in dementia caused by Alzheimer’s disease.However,the mechanis...
关键词:nerve REGENERATION Alzheimer’s disease SYNAPTIC plasticity hippocampus learning and memory long-term POTENTIATION βamyloid glutamate receptor SYNAPTIC strength neural REGENERATION 
Rapid transport of insulin to the brain following intranasal administration in rats
《中国神经再生研究:英文版》2019年第6期1046-1051,共6页Lir-Wan Fan Kathleen Carter Abhay Bhatt Yi Pang 
Michael.J.Fox Foundation(to YP).
We previously reported that intranasal insulin protects substantia nigra dopaminergic neurons against 6-hydroxydopamine neurotoxicity in rats.This study aimed to assess insulin pharmacokinetics in the rat brain follow...
关键词:DOPAMINERGIC neurons STRIATUM substantia nigra brainstem olfactory bulb GLIA TRIGEMINAL nerve pharmacokinetics AXONAL TRANSPORT pAkt 
A method to deliver patterned electrical impulses to Schwann cells cultured on an artificial axon
《中国神经再生研究:英文版》2019年第6期1052-1059,共8页Antonio Merolli Yong Mao Gregory Voronin Joseph A.M.Steele N.Sanjeeva Murthy Joachim Kohn 
supported by the New Jersey Health Foundation under Grant#PC94-17;the National Institute of Biomedical Imaging And Bioengineering of the National Institutes of Health under Award Number P41EB001046(both to JK).
Information from the brain travels back and forth along peripheral nerves in the form of electrical impulses generated by neurons and these impulses have repetitive patterns.Schwann cells in peripheral nerves receive ...
关键词:Schwann cell carbon fiber MYELINATION ELECTRICAL impulse artificial AXON in vitro system Arduino MICROCONTROLLER MYELIN basic protein 
Use of a combination strategy to improve neuroprotection and neuroregeneration in a rat model of acute spinal cord injury
《中国神经再生研究:英文版》2019年第6期1060-1068,共9页Elisa García Roxana Rodríguez-Barrera Vinnitsa Buzoianu-Anguiano Adrian Flores-Romero Emanuel Malagón-Axotla Marco Guerrero-Godinez Estefanía De la Cruz-Castillo Laura Castillo-Carvajal Monserrat Rivas-Gonzalez Paola Santiago-Tovar Ivis Morales Cesar Borlongan Antonio Ibarra 
the National Council of Science and Technology of Mexico(CONACYT),No.178544(to AI).
Spinal cord injury is a very common pathological event that has devastating functional consequences in patients.In recent years,several research groups are trying to find an effective therapy that could be applied in ...
关键词:FIBRIN GLUE mesenchymal stem cells GLIAL scar protective AUTOIMMUNITY NEURAL derived peptides NEURAL regeneration 
Motor inhibition efficiency in healthy aging:the role of γ-aminobutyric acid
《中国神经再生研究:英文版》2019年第5期741-744,共4页Lisa Pauwels Celine Maes Lize Hermans Stephan P.Swinnen 
the Research Foundation Flanders(G089818N;to SPS);the Excellence of Science grant(EOS,30446199,MEMODYN;to SPS);the KU Leuven Research Fund(C16/15/070;to SPS);the postdoctoral fellowship from the Research Fund KU Leuven(PDM/18/180;to LP);an aspirant fellowship of the Research Foundation– Flanders(FWO)to CM.
The ability to cancel a motor response is critical for optimal functioning in various facets of daily life.Hence,efficient inhibitory motor control is a key function throughout the lifespan.Considering the fact that i...
关键词:PROACTIVE INHIBITION reactive INHIBITION motor INHIBITION healthy aging gamma-aminobutyric acid magnetic resonance spectroscopy GABA INHIBITORY NEUROTRANSMITTER NEUROIMAGING 
Early constraint-induced movement therapy affects behavior and neuronal plasticity in ischemia-injured rat brains
《中国神经再生研究:英文版》2019年第5期775-782,共8页Xi-Hua Liu Hong-Yan Bi Jie Cao Shuo Ren Shou-Wei Yue 
the Natural Science Foundation of Shandong Province of China,No.2014ZRB14502(to XHL).
Constraint-induced movement therapy is an effective rehabilitative training technique used to improve the restoration of impaired upper extremity movement after stroke.However,whether constraint-induced movement thera...
关键词:NERVE REGENERATION ischemic stroke rehabilitation constraint-induced movement therapy NERVE growth factors functional recovery NEURONAL PLASTICITY real time-polymerase chain reaction western blot assay rats neural REGENERATION 
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