对非梗阻性无精症实施AMH检测的临床应用价值评估  

Evaluation of clinical application value of AMH test for non-obstructive azoospermia

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作  者:杨敬虞 Jingyu YANG (Chengdu Xinan Women's Hospital, Chengdu 610000, China)

机构地区:成都西囡妇科医院,四川成都610000

出  处:《临床检验杂志(电子版)》2019年第1期21-23,共3页Clinical Laboratory Journal(Electronic Edition)

摘  要:目的研究对非梗阻性无精症实施AMH检测的临床应用价值.方法选择我院2016年4月-2018年4月正常生育、梗阻性无精子症(OA)、非梗阻性无精症(NOA)患者各50例进行研究,均接受血清促卵泡激素(FSH)、睾酮(T)浓度、抗缪勒管激素(AMH)浓度测定,分析效果.结果NOA组TV、AMH明显更低,FSH明显更高(P〈0.05),T指标水平与OA组、正常生育组差异不明显(P〉0.05);精浆AMH用于区分NOA患者TESE成功与否的准确性、阳性预测值、阳性似然比均明显更高,阴性似然比明显更低(P〈0.05).结论精浆AMH用于判断非梗阻性无精症患者睾丸精子获取术是否成功具有重要价值.Objective To study the clinical value of AMH detection in non-obstructive azoospermia. Methods A total of 50 patients with normal fertility, obstructive azoospermia (OA), and non-obstructive azoospermia (NOA) were enrolled in our hospital from April 2016 to April 2018. All of them received serum follicle stimulating hormone (FSH), testosterone (T) concentration, anti-mullerian hormone (AMH) concentration determination. Results The TV and AMH in the NOA group were signifcantly lower, and the FSH was signifcantly higher (P〈0.05). The difference between the T index and the OA group and the normal fertility group was not signifcant (P〉0.05). The seminal plasma AMH was used to distinguish the success of TESE in NOA patients. The accuracy, positive predictive value, and positive likelihood ratio were signifcantly higher, and the negative likelihood ratio was signifcantly lower (P〈0.05). Conclusion Seminal plasma AMH is of great value in judging the success of testicular sperm acquisition in patients with non-obstructive azoospermia.

关 键 词:非梗阻性无精症 抗缪勒管激素 检测 

分 类 号:R698.205[医药卫生—泌尿科学;医药卫生—临床医学;医药卫生—外科学]

 

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